Fragmin Injection In Pakistan

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Fragmin injection uses

Fragmin is used for the following purposes:

1. Preventing Blood Clots: It helps prevent the formation of blood clots in patients who are at risk, such as those undergoing surgery, bedridden due to illness, or with certain medical conditions like cancer.
2. Treating Blood Clots: Fragmin is also used to treat existing blood clots, such as deep vein thrombosis (DVT) and pulmonary embolism (PE), by thinning the blood to prevent the clots from getting bigger or spreading to other parts of the body.
3. Preventing Clotting in Dialysis: It is often used during kidney dialysis to avoid blood clots in the dialysis machine.
4. Managing Blood Clot Risks in Cancer Patients: Fragmin is prescribed to reduce the risk of blood clots in cancer patients who are more prone to clotting complications.

Fragmin injection uses in Urdu

کا ​​استعمال مندرجہ ذیل مقاصد کے لیے کیا جاتا ہےFragmin

خون کے جمنے کی روک تھام: یہ ایسے مریضوں میں خون کے جمنے کی تشکیل کو روکنے میں مدد کرتا ہے جو خطرے میں ہیں، جیسے کہ سرجری سے گزرنے والے، بیماری کی وجہ سے بستر پر پڑے ہوئے، یا کینسر جیسی بعض طبی حالتوں میں۔
خون کے جمنے کا علاج: موجودہ خون کے لوتھڑے کے علاج کے لیے بھی استعمال کیا جاتا ہے، جیسے ڈیپ وین تھرومبوسس  اور پلمونری ایمبولزم خون کو پتلا کرکے جمنے کو بڑھنے یا جسم کے دوسرے حصوں میں جانے سے روکتا ہے۔
ڈائیلاسز میں جمنے کی روک تھام: یہ اکثر کڈنی ڈائیلاسز کے دوران ڈائیلاسز مشین میں خون کے جمنے سے بچنے کے لیے استعمال کیا جاتا ہے۔
کینسر کے مریضوں میں خون کے جمنے کے خطرات کا انتظام: فریگمین کو کینسر کے مریضوں میں خون کے جمنے کے خطرے کو کم کرنے کے لیے تجویز کیا جاتا ہے جو جمنے کی پیچیدگیوں کا زیادہ شکار ہوتے ہیں۔

Fragmin injection dosage

The dosage of Fragmin (dalteparin sodium) injection varies depending on the specific condition being treated, the patient’s weight, and other medical factors. Below are general dosage guidelines:

Prevention of Deep Vein Thrombosis (DVT) in Surgery

Moderate-risk patients: 2,500 to 5,000 IU administered subcutaneously 1-2 hours before surgery, then daily for 5-10 days.
High-risk patients: 5,000 IU the evening before surgery, followed by 5,000 IU daily.

Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)

Initial treatment: 100 IU/kg body weight subcutaneously every 12 hours or 200 IU/kg body weight once daily.
Treatment typically continues for 5-10 days, followed by oral anticoagulation.

Prevention of Clotting in Hemodialysis

Patients with normal kidney function: 5,000 IU administered subcutaneously once daily during dialysis sessions.
For patients with kidney issues: The dosage may be adjusted according to the patient’s condition and dialysis needs.

Prevention of Clotting in Cancer Patients

First month: 200 IU/kg body weight once daily, not exceeding 18,000 IU per dose.
Subsequent months: 150 IU/kg body weight once daily for 2-6 months

Fragmin injection side effects

Fragmin (dalteparin sodium) injection may cause some side effects. While many people experience minimal issues, it’s important to be aware of potential reactions. Common and serious side effects include:

Common Side Effects

• Bruising or Pain at the Injection Site: Mild discomfort, redness, or swelling where the injection was given.
• Bleeding: Minor bleeding, such as nosebleeds, bleeding gums, or prolonged bleeding from cuts.
• Elevated Liver Enzymes: Slight increases in liver function tests, usually detected during routine blood tests.

Serious Side Effects (Seek Medical Attention)

• Severe Bleeding: Unusual or excessive bleeding, such as blood in the urine, stool, or vomit, heavy menstrual bleeding, or unexpected bruising.
• Allergic Reactions: Rash, itching, swelling, dizziness, or difficulty breathing, which may indicate an allergic response.
• Low Platelet Count (Thrombocytopenia): Signs include unusual bleeding or bruising and could indicate a condition called heparin-induced thrombocytopenia (HIT).
• Spinal/Epidural Hematoma: Patients receiving spinal or epidural anesthesia while on Fragmin may develop a blood clot in the spinal area, leading to potential paralysis. Signs include back pain, numbness, or muscle weakness.

Rare Side Effects

• Bone Thinning (Osteoporosis): Prolonged use of Fragmin may lead to a reduction in bone density.
• Hyperkalemia: Elevated potassium levels in the blood, which may cause symptoms like muscle weakness, fatigue, or irregular heartbeats.

Precautions and Warnings

While using fragmin injection it is essential to be aware of certain precautions and warnings:

1. Bleeding Risk: Increased risk of bleeding, especially with ulcers, recent surgery, or bleeding disorders. Caution if taking other blood thinners.
2. Spinal/Epidural Hematoma: Risk of serious spinal blood clots during spinal procedures. Inform your provider if you have these procedures planned.
3. Low Platelet Count: This can cause decreased platelet levels (HIT). Regular blood tests are needed.
4. Kidney Function: It requires dose adjustments in patients with kidney impairment.
5. Pregnancy and Breastfeeding: Generally safe during pregnancy but use under medical supervision. Consult your doctor if breastfeeding.

Price in Pakistan

Fragmin injection is available for Rs/5,258.92 in Pakistan.